Cryo-EM structure of VASH1-SVBP bound to microtubules
Li F, Li Y, Ye X, Gao H, Shi Z, Luo X, Rice LM, and Yu H
eLife 2020 August
[Pubmed]
Insights into allosteric control of microtubule dynamics from a buried β-tubulin mutation that causes faster growth and slower shrinkage
Ye, XY, Kim T, Geyer, EA, and Rice LM
Protein Science 2020 June
[Pubmed]
Long-range, through-lattice coupling improves predictions of microtubule catastrophe
Kim T, and Rice LM
Molecular Biology of the Cell 2019 June
[Pubmed]
Direct observation of individual tubulin dimers binding to growing microtubules
Mickolajczyk, KJ, Geyer EA, Kim T, Rice LM, and Hancock WO
PNAS 2019 April
[Pubmed]
Design principles of a microtubule polymerase
Geyer EA, Miller MP, Brautigam CA, Biggins S, and Rice LM
eLife 2018 June
[Pubmed]
An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue
Majumdar S, Kim T, Chen Z, Munyoki S, Tso SC, Brautigam CA, Rice LM
Molecular Biology of the Cell 2018 April
[Pubmed]
Microtubule dynamics: an interplay of biochemistry and mechanics
Brouhard GJ and Rice LM
Nature Reviews Molecular and Cell Biology 2018 July
[Pubmed]
Structural and functional differences between porcine brain and budding yeast microtubules
Howes SC, Geyer EA, LaFrance B, Zhang R, Kellogg EA, Westermann S, Rice LM, and Nogales E
Cell Cycle 2018 January
[Pubmed]
A tubulin binding switch underlies Kip3/Kinesin-8 depolymerase activity
Arellano-Santoyo H, Geyer EA, Stokasimov E, Chen G-Y, Su X, Hancock W, Rice LM, and Pellman D
Developmental Cell 2017 July;
[Pubmed]
Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips
Driver JW, Geyer EA, Bailey M, Rice LM, and Asbury CA
eLife 2017 June;
[Pubmed]
Structural differences between yeast and mammalian microtubules revealed by cryo-EM
Howes SC, Geyer EA, LaFrance B, Zhang R, Kellogg EA, Westermann S, Rice LM, and Nogales E
J Cell Biol 2017 June;
[Pubmed]
GDP to GTP exchange on the microtubule end can contribute to the frequency of catastrophe
Piedra FA, Kim T, Garza ES, Geyer EA, Burns A, Ye X, and Rice LM
Mol Biol Cell 2016 May;
[Pubmed]
A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics
Geyer EA, Burns A, Lalonde BA, Ye X, Piedra FA, Huffaker TC, and Rice LM
eLife 2015 Oct; 4:e10113
[Pubmed]
The contribution of ab-tubulin curvature to microtubule dynamics
Brouhard GJ and Rice LM
J Cell Biology 2014 Nov; 207:323-334
[Pubmed]
A tethered delivery mechanism explains the catalytic action of a microtubule polymerase
Azaz P, Munyoki S, Geyer EA, Piedra FA, Vu ES, Bromberg R, Orwinowski Z, Grishin NV, Brautigam CA, and Rice LM
eLife 2014 August 5; 3:e03069
[Pubmed]
Regulation of microtubule motors by tubulin isotypes and post-translational modifications
Sirajuddin M, Rice LM, and Vale RD
Nature Cell Biology 2014 April; 16:335-44
[Pubmed]
A TOG:ab-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase
Azaz P, Ye X, Huddleston P, Brautigam CA, and Rice LM
Science 2012 August 17; 337:857-860
[Pubmed]
Design, over expression, and purification of polymerization-blocked yeast ab-tubulin mutants
Johnson V, Ayaz P, Huddleston P, and Rice LM
Biochemistry 2011 Oct 11; 50(40):8636-44.
[Pubmed]
The lattice as allosteric effector: structural studies of alpha/beta- and gamma-tubulin clarify the role of GTP in microtubule assembly
Rice LM, Montabana E, and Agard DA
Proc Natl Acad Sci USA 2008 Apr 8; 105(14):5378-83.
[Pubmed]
The structure of the gamma-tubulin small complex: implications of its architecture and flexibility for microtubule nucleation
Kollman JW, Zelter A, Muller EG, Fox B, Rice LM, Davis TN, and Agard DA
Mol Biol Cell 2008 Jan; 19(1):207-15.
[Pubmed]
Insights into microtubule nucleation from the crystal structure of human gamma-tubulin
Aldaz H, Rice LM, Stearns T, and Agard DA
Nature 2005 May 26; 435(7041):523-7. doi: 10.1083/jcb.201407095
[Pubmed]
